Prof. Takafira Mduluza

Qualifications:

PhD Biochemical immunology and parasitology (University of Glasgow, UK); MPhil Biochemical Immunology of parasitic infections (UZ); BSc Applied Biology and Biochemistry (UZ)

Academic Appointments:

Senior Lecturer

Research Interests:

Molecular Immunology
Immuno-epidemiology
Infectious disease
Cellular immunity
Malaria
Schistosomiasis
HIV/AIDS
Vaccines.

Faculty: Science

Department: Biotechnology and Biochemistry

Research Category: Bioscience

Biography:

Takafira Mduluza graduated from University of Zimbabwe with degrees in Applied Biology and Biochemistry and Master of Philosophy in Biochemical Immunology of parasitic infections. After an internship at Blair Research Institute, Ministry of Health and Child Welfare he studied for a PhD in biochemical immunology and parasitology in the Department of Infection and Immunity at the University of Glasgow, UK. His work was on Biochemical Immuno-epidemiology of schistosomiasis at humoral and cellular level. He began working on the immunology of schistosomiasis in 1992, as a member of the senior scientific staff at the Blair Research Laboratories (National Institute of Health Research) in Zimbabwe. In 1999, Takafira moved to the University of Zimbabwe as a Lecturer.

Email: mduluza@medic.uz.ac.zw

Phone: +263 242 303211

Publications:

1. Imai, N., Rujeni, N., Nausch, N., Bourke, C. D., Appleby, L. J., Cowan, G., ... & Mutapi, F. (2011). Exposure, infection, systemic cytokine levels and antibody responses in young children concurrently exposed to schistosomiasis and malaria. Parasitology, 138(12), 1519-1533.
2. Midzi, N., Mtapuri-Zinyowera, S., Sangweme, D., Paul, N. H., Makware, G., Mapingure, M. P., ... & Mduluza, T. (2011). Efficacy of integrated school based de-worming and prompt malaria treatment on helminths-Plasmodium falciparum co-infections: A 33 months follow up study. BMC international health and human rights, 11(1), 1-14.
3. Midzi, N., Mtapuri-Zinyowera, S., Mapingure, M. P., & Paul, N. H. (2011). Knowledge Attitudes and Practices of grade three primary schoolchildren in relation to. Issue: BMC Infectious Diseases, 11 (1).
4. Mutapi, F., Rujeni, N., Bourke, C., Mitchell, K., Appleby, L., Nausch, N., ... & Mduluza, T. (2011). Schistosoma haematobium treatment in 1–5 year old children: safety and efficacy of the antihelminthic drug praziquantel. PLoS Negl Trop Dis, 5(5), e1143.

5. Mutapi, F., Imai, N., Nausch, N., Bourke, C. D., Rujeni, N., Mitchell, K. M., ... & Mduluza, T. (2011). Schistosome infection intensity is inversely related to auto-reactive antibody levels. PLoS One, 6(5), e19149.
6. Arkestål, K., Sibanda, E., Thors, C., Troye-Blomberg, M., Mduluza, T., Valenta, R., ... & van Hage, M. (2011). Impaired allergy diagnostics among parasite-infected patients caused by IgE antibodies to the carbohydrate epitope galactose-α1, 3-galactose. Journal of Allergy and Clinical Immunology, 127(4), 1024-1028.
7. Nausch, N., Midzi, N., Mduluza, T., Maizels, R. M., & Mutapi, F. (2011). Regulatory and activated T cells in human Schistosoma haematobium infections. PloS one, 6(2), e16860.
8. Mutapi, F., Bourke, C., Harcus, Y., Midzi, N., Mduluza, T., Turner, C. M., ... & Maizels, R. M. (2011). Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4. Parasite immunology, 33(3), 181-192.
9. Sangweme, D. T., Midzi, N., Zinyowera-Mutapuri, S., Mduluza, T., & Diener-West, M. (2010). Impact of Schistosome Infection on Plasmodium falciparum. pntd. 0000882.
10. Mduluza, T., Mutapi, F., Ruwona, T., Kaluka, D., Midzi, N., & Ndhlovu, P. D. (2009). Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection. Malawi Medical Journal, 21(4).